Recombinant HMGB2 anticorps

N° du produit ABIN7828260

Cet anticorps anti-HMGB2 Monoclonal Lapin (Clone A533) (ABIN7828260) détecte spécifiquement HMGB2 dans WB, IHC, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant HMGB2 anticorps (ABIN7828260)

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HMGB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A533

Détail du produit anti-HMGB2 anticorps

Fonction: Recombinant HMGB2 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human HMGB2 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,IP 1:25-1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur HMGB2

Antigène: HMGB2 (High Mobility Group Box 2 (HMGB2))

Autre désignation: HMGB2

Sujet: HMGB,High mobility group box,High mobility group (nonhistone chromosomal) protein,HMG B,HMG,HMGB2,HMG2,C80539,High mobility group (nonhistone chromosomal) protein 2,High mobility group box 2,High mobility group protein 2,High mobility group protein B2,HMG 2,HMG B2,HMG-2,HMGB2 belongs to a family of highly conserved proteins that contain HMG box domains. HMGB2 is widely expressed during embryonic development, but it is restricted to lymphoid organs and testis in adult animals. HMGB2 facilitate the binding of Hox proteins, Oct proteins, p53, Rel proteins, and steroid hormone receptor proteins to their target gene promoters. Furthermore, HMGB2 interacts with RAG1 to facilitate RAG complex binding to the recombinant signal sequence (RSS) and stimulate DNA-bending and subsequent VDJ cleavage at antigen receptor genes. In addition to their functions in the nucleus, HMGB proteins play a significant role in extracellular signaling associated with inflammation. HMGB2 is secreted by myeloid cells and promotes proliferation and migration of endothelial cells by binding to the receptor for advanced glycation end products (RAGE). Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 24 kDa

Observed MW: 24 kDa

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin