Recombinant KDM2A anticorps

N° du produit ABIN7828363

Cet anticorps Lapin Monoclonal détecte spécifiquement KDM2A dans WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant KDM2A anticorps (ABIN7828363)

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KDM2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A401

Détail du produit anti-KDM2A anticorps

Fonction: Recombinant KDM2A Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human KDM2A fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000-1:5000,IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur KDM2A

Antigène: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Autre désignation: KDM2A

Sujet: CXXC,FBXL,KIAA,FBL,KDM2A,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,KIAA1004,CXXC8,FBL11,FBL7,FBXL11,JHDM1A,LILINA,lysine demethylase 2A,[Histone-H3]-lysine-36 demethylase 1A,CXXC-type zinc finger protein 8,F box / LRR repeat protein 11,F box and leucine rich repeat protein 11,F box protein FBL7,F-box and leucine-rich repeat protein 11,F-box protein FBL7,F-box protein Lilina,F-box/LRR-repeat protein 11,JmjC domain-containing histone demethylation protein 1A,Jumonji C domain containing histone demethylase 1A,Lysine (K) specific demethylase 2A,Lysine-specific demethylase 2A,Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and Trimethylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 133 kDa

Observed MW: 140 kDa The actual band is not consistent with the expectation.

UniProt: Q9Y2K7

Pathways: L'effet Warburg