Recombinant MYH7 anticorps

N° du produit ABIN7828412

L’anticorps anti-MYH7 Monoclonal Lapin est utilisé pour la détection de MYH7 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC.

Aperçu rapide pour Recombinant MYH7 anticorps (ABIN7828412)

Antigène: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MYH7 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: A707

Détail du produit anti-MYH7 anticorps

Fonction: Recombinant MYH7 Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: IHC 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur MYH7

Antigène: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Autre désignation: MYH7

Sujet: CMH,MPD,MYH,myosin,MYH7,CMD1S,CMH1,MPD1,MYHCB,SPMD,SPMM,myosin-7,PVALB,Nonmuscle myosin is an actin-based motor protein essential to cell motility, cell division, migration, adhesion, and polarity. The holoenzyme consists of two identical heavy chains and two sets of light chains. The light chains (MLCs) regulate myosin II activity and stability. The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10, and MYH14, which generate three different nonmuscle myosin II isoforms, IIa,IIb, and IIc, respectively. While all three isoforms perform the same enzymatic tasks, binding to and contracting actin filaments coupled to ATPhydrolysis, their cellular functions do not appear to be redundant and they have different subcellular distributions. The carboxy-terminal taildomain of myosin II is important in isoform-specific subcellular localization. Research studies have shown that phosphorylation of myosin IIa at Ser1943 contributes to the regulation of breast cancer cell migration. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P12883