MYH7 anticorps (AA 1766-1935)

N° du produit ABIN6144239

Détail du produit anti-MYH7 anticorps

Antigène: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Épitope: AA 1766-1935

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYH7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: AEELKKEQDT SAHLERMKKN MEQTIKDLQH RLDEAEQIAL KGGKKQLQKL EARVRELENE LEAEQKRNAE SVKGMRKSER RIKELTYQTE EDRKNLLRLQ DLVDKLQLKV KAYKRQAEEA EEQANTNLSK FRKVQHELDE AEERADIAES QVNKLRAKSR DIGTKGLNEE

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1766-1935 of human MYH7/beta-MHC (NP_000248.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-MYH7 (ABIN6144239)

Kumar, Wang, Liu, Ding, Dong, Zheng, Ye, Liu: "Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." dans: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." dans: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Détails sur MYH7

Antigène: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Autre désignation: MYH7 (MYH7 Produits)

Synonymes: anticorps CMD1S, anticorps CMH1, anticorps MPD1, anticorps MYHCB, anticorps SPMD, anticorps SPMM, anticorps Myhcb, anticorps AMHC1, anticorps myosin, anticorps myosin-7, anticorps B-MHC, anticorps MyHC-I, anticorps Myhc-b, anticorps beta-MHC, anticorps myosin heavy chain 7, anticorps myosin, heavy chain 7, cardiac muscle, beta, anticorps myosin, heavy polypeptide 7, cardiac muscle, beta, anticorps MYH7, anticorps Myh7

Sujet: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.,MYH7,CMD1S,CMH1,MPD1,MYHCB,SPMD,SPMM,myosin-7,MYH7,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYH7

Poids moléculaire: 223 kDa

ID gène: 4625

UniProt: P12883