Recombinant PNKP anticorps

N° du produit ABIN7828469

L’anticorps anti-PNKP Monoclonal Lapin est utilisé pour la détection de PNKP dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant PNKP anticorps (ABIN7828469)

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PNKP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A752

Détail du produit anti-PNKP anticorps

Fonction: Recombinant PNKP Monoclonal Antibody

Purification: Protein A purified

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:2000,IHC 1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP

Sujet: AOA,EIEE,PNKP,AOA4,EIEE10,MCSZ,PNK,PNK (polynucleotide kinase) is a DNA repair enzyme that participates in single strand break repair and non-homologous end rejoining (NHEJ) for double strand breaks. PNK possesses a 5'-DNA kinase activity and a 3'-DNA phosphatase activity. It has three domains, a C terminal kinase domain, a central phosphatase domain, and an N-terminal forkhead associated (FHA) domain that is responsible for protein protein interactions. Reduction in expression of PNK by RNAi sensitizes cells to ionizing radiation and topoisomerase I inhibitors. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 57 kDa

Observed MW: 60 kDa The actual band is not consistent with the expectation.

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation