Recombinant SIRT6 anticorps

N° du produit ABIN7828568

L’anticorps anti-SIRT6 Monoclonal Lapin est utilisé pour la détection de SIRT6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour Recombinant SIRT6 anticorps (ABIN7828568)

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT6 est non-conjugé

Application: Western Blotting (WB)

Clone: A547

Détail du produit anti-SIRT6 anticorps

Fonction: Recombinant SIRT6 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human SIRT6 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur SIRT6

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Autre désignation: SIRT6

Sujet: SIRT,SIR2L,sirtuin,SIR2L6,SIRT6,sirtuin 6,SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway. The BER pathway repairs single-stranded DNA lesions that arise spontaneously from endogenous alkylation, oxidation, and deamination events. SirT6 deficient mice show increased sensitivity to DNA-damaging agents, including the alkylating agents MMS and H2O2. In addition, these mice show genome instability with increased frequency of fragmented chromosomes, detached centromeres, and gaps. SirT6 may regulate the BER pathway by deacetylating DNA Polβ or other core components of the pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 39 kDa

Observed MW: 42 kDa The actual band is not consistent with the expectation.

UniProt: Q8N6T7