Recombinant Topoisomerase I anticorps

N° du produit ABIN7828628

L’anticorps anti-Topoisomerase I Monoclonal Lapin est utilisé pour la détection de Topoisomerase I dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, IF, IP et FACS.

Aperçu rapide pour Recombinant Topoisomerase I anticorps (ABIN7828628)

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Topoisomerase I est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: A475

Détail du produit anti-Topoisomerase I anticorps

Fonction: Recombinant Topoisomerase I Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Topoisomerase I fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000,IHC 1:100-1:500,IF 1:50,FCM 1:50-1:100,IP 1:25-1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur Topoisomerase I

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Autre désignation: Topoisomerase I

Sujet: TOP,TOP1,TOPI,DNA topoisomerases play essential roles in many DNA metabolic processes including DNA repair. Topoisomerases can introduce DNA damage upon exposure to drugs that stabilize the covalent protein-DNA intermediate of the topoisomerase reaction. Lesions in DNA are also able to trap topoisomerase-DNA intermediates. DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a mechanism of transient DNA strand cleavage characterized by the formation of a phosphotyrosyl bond between the DNA end and active site tyrosine. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 91 kDa

Observed MW: 108 kDa The actual band is not consistent with the expectation.

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance