Recombinant TPX2 anticorps

N° du produit ABIN7828630

Cet anticorps Lapin Monoclonal détecte spécifiquement TPX2 dans WB, IHC, IF et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant TPX2 anticorps (ABIN7828630)

Antigène: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TPX2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A382

Détail du produit anti-TPX2 anticorps

Fonction: Recombinant TPX2 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human TPX2 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:1000,IHC 1:50-1:200,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur TPX2

Antigène: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Autre désignation: TPX2

Sujet: FLS,HCA,TPX,HCTP,REPP,GD:C20orf,DIL,DIL2,p100,DIL-2,HCTP4,FLS353,HCA519,REPP86,C20orf1,C20orf2,GD:C20orf1,TPX2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in lung cells,Differentially expressed in lung cells 2,DIL 2,HCA 519,HCTP 4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules.Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha .At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 86 kDa

Observed MW: 100 kDa The actual band is not consistent with the expectation.

UniProt: Q9ULW0