Recombinant UBE2K anticorps

N° du produit ABIN7828658

L’anticorps anti-UBE2K Monoclonal Lapin est utilisé pour la détection de UBE2K dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Recombinant UBE2K anticorps (ABIN7828658)

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp UBE2K est non-conjugé

Application: Western Blotting (WB)

Clone: A412

Détail du produit anti-UBE2K anticorps

Fonction: Recombinant HIP2/LIG Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human HIP2/LIG fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur UBE2K

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Autre désignation: HIP2/LIG

Sujet: HIP,UBC,UBE2K,E2-25K,HIP2,HYPG,LIG,UBC1,HIP-2,Huntingtin-Interacting Protein 2,Ubiquitin Carrier Protein,Ubiquitin-Conjugating Enzyme E2 K,Ubiquitin-Conjugating Enzyme E2(25K),Ubiquitin-Conjugating Enzyme E2-25 kDa,Ubiquitin-Conjugating Enzyme E2-25K,Ubiquitin-Protein Ligase,Huntingtin-interacting protein 2 (HIP2/LIG), is a E2 ubiquitin-conjugating enzyme, which accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, HIP2/LIG catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, while it does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Moreover, HIP2/LIG mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 22 kDa

Observed MW: 22 kDa

UniProt: P61086