MERTK anticorps

N° du produit ABIN7828913

L’anticorps anti-MERTK Monoclonal Souris est utilisé pour la détection de MERTK dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour MERTK anticorps (ABIN7828913)

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MERTK est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 590H11G1E3

Détail du produit anti-MERTK anticorps

Fonction: Purified Anti-Human MER Antibody[590H11G1E3]

Purification: >98%, Protein A/G purified

Pureté: >98 %

Immunogène: Recombinant Human MER protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: FCM 2 μg/mL(0.5x106-1x106 cells)

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur MERTK

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Autre désignation: MER

Sujet: Tyro,MERTK,MER,RP38,Tyro12,c-Eyk,c-mer,Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK,Tyrosine-protein kinase Mer,MERTK plays a role in the retinal pigment epithelium as a regulator of rod outer segments fragments phagocytosis. MERTK also plays a role in the inhibition of Toll-like receptor-mediated innate immune responses through the activation of STAT1. Upregulation of MERTK seems to also promote the survival of certain cancer cells, such as t(1,19)-positive acute lymphoblastic leukemias (ALL). MERTK also has a role in cellular migration, as MERTK KO macrophages demonstrate cytoskeletal disruptions that impacts its shape and directional migration. Melanoma cells express high levels of MERTK, which makes this molecule an attractive therapeutic target. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q12866

Pathways: Signalisation RTK