GLO1 anticorps
Aperçu rapide pour GLO1 anticorps (ABIN7833275)
Antigène
Voir toutes GLO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-GLO1 | Glyoxalase I (clone 6F10)
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Réactivité croisée (Details)
- Human, simian, mouse
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Stérilité
- Sterile filtered
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Immunogène
- Recombinant
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Isotype
- IgG2b kappa
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Indications d'application
- 1 : 1000 (WB)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Proprietary affinity chromatography in PBS. Contains 50 % glycerol, filter sterilized.
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Conseil sur la manipulation
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- GLO1 (Glyoxalase I (GLO1))
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Autre désignation
- GLO1
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Sujet
- Glyoxalase I (GLO1) is an enzyme that plays a role in the detoxification of methylglyoxal (MG), a side-product of glycolysis, via condensation with glutathione to produce S-lactoyl-glutathione. GLO1 is a zinc metalloenzyme whose crystal structure has been solved. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric and its sequence is well conserved. GLO1 is found over-expressed in some tumors. GLO1 has also been suggested to be involved in anxiety diseases, autism, and Alzheimer's disease.
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Poids moléculaire
- 27 kDa (mouse, 29 kDa (human, simian)
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ID gène
- 109801
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UniProt
- Q9CPU0
Antigène
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