RPA1 anticorps
Aperçu rapide pour RPA1 anticorps (ABIN7833814)
Antigène
Voir toutes RPA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Anti-RFa1/Rpa1 | Replication factor protein 1 (Saccharomyces cerevisiae)
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Réactivité croisée (Details)
- Saccharomyces cerevisiae
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Immunogène
- Purified
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Indications d'application
- 1: 200 (IP), 1 : 2000 (WB)
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Serum. Contains 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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Autre désignation
- RFa1/Rpa1
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Sujet
- Rfa1 (Replication Factor A protein 1) as part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
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Poids moléculaire
- 70.3 kDa
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ID gène
- 851266
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UniProt
- P22336
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Pathways
- Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Antigène
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