Recombinant EPH Receptor B4 anticorps (AA 1-200)
Aperçu rapide pour Recombinant EPH Receptor B4 anticorps (AA 1-200) (ABIN7857601)
Antigène
Voir toutes EPH Receptor B4 (EPHB4) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-200
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Expression System
- CHO Cells
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Fonction
- Recombinant EPH Receptor B4 (EPHB4) Antibody
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Specificité
- The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Recombinant fragment (around aa1-200) of human EPHB4 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- EPH Receptor B4 (EPHB4)
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Autre désignation
- EPH Receptor B4
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Sujet
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Ephrin receptor EphB4, Ephrin type-B receptor 4, Hepatoma Transmembrane Kinase, HTK, MYK1, TYRO11, Tyrosine-protein kinase receptor HTK, Tyrosine-protein kinase TYRO11
Human tonsil, hepatocellular carcinoma or histiocytoma. Lung, Skin, Spleen
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Poids moléculaire
- 120kDa
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ID gène
- 2050, 437008
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UniProt
- P54760
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Pathways
- Signalisation RTK
Antigène
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