Recombinant MUC4 anticorps (AA 1729-1860)

N° du produit ABIN7857631

Cet anticorps anti-MUC4 Monoclonal Lapin (Clone MUC4-8660R) (ABIN7857631) détecte spécifiquement MUC4 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant MUC4 anticorps (AA 1729-1860) (ABIN7857631)

Antigène: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MUC4-8660R

Détail du produit anti-MUC4 anticorps

Épitope: AA 1729-1860

Expression System: CHO Cells

Fonction: Recombinant MUC4 (Mucin 4 / Gastric Mucin) Antibody

Specificité: The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Recombinant fragment (around aa 1729-1860) of human MUC4 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC4

Antigène: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Autre désignation: MUC4 Mucin 4

Sujet:

Ascites sialoglycoprotein 1 / 2, ASGP, ASGP-1, ASGP-2, MUC-4, MUC4, Mucin 4 cell surface associated, Mucin 4 tracheobronchial, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin

Human stomach, colon or esophagus.

Poids moléculaire: 235kDa

ID gène: 4585, 369646

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity