Recombinant Cathepsin G anticorps (N-Term)
Aperçu rapide pour Recombinant Cathepsin G anticorps (N-Term) (ABIN7865475)
Antigène
Voir toutes Cathepsin G (CTSG) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- N-Term
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Expression System
- CHO Cells
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Fonction
- Recombinant Cathepsin G (Neutrophil Marker) Antibody
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Specificité
- Cathepsins are members of the papain family of cysteine proteases which are involved in a variety of physiological processes such as proenzyme activation, enzyme inactivation, antigen presentation, hormone maturation, tissue remodeling and bone matrix resorption. Cathepsin G is a 29 kD serine protease and is located in neutrophilic polymorphonuclear leukocytes which contain specialized azurophil granules together with two other serine proteases, elastase and protease 3. These three proteases may participate in the killing and digestion of engulfed pathogens and in connective tissue remodeling at sites of inflammation. Cathepsin G has also been found to be essential for the induction of human natural killer cell cytotoxicity.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Prokaryotic recombinant protein corresponding to a 124 amino acid N-terminal region of the cathepsin G molecule
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Cathepsin G (CTSG)
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Autre désignation
- Cathepsin G
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Sujet
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CATG
THP-1 cells. Human bone marrow or lymphoid tissue.
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Poids moléculaire
- 32kDa
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ID gène
- 1511
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UniProt
- P08311
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
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