Recombinant Renal Cell Carcinoma (Gp200) (AA 80-100), (N-Term) anticorps

N° du produit ABIN7865169

Cet anticorps Lapin Monoclonal détecte spécifiquement Renal Cell Carcinoma (Gp200) dans IHC et WB. Il présente une réactivité avec des échantillons de Humain, Rat et Cobaye.

Aperçu rapide pour Recombinant Renal Cell Carcinoma (Gp200) (AA 80-100), (N-Term) anticorps (ABIN7865169)

Antigène: Renal Cell Carcinoma (Gp200)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Cobaye

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: CA9-9621R

Détail du produit

Épitope: AA 80-100, N-Term

Expression System: CHO Cells

Fonction: Recombinant Renal Cell Carcinoma (Carbonic Anhydrase IX) Antibody

Specificité: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Extracellular N-terminal proteoglycan-like region. Epitope is between aa80-100.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détail du antigène

Antigène: Renal Cell Carcinoma (Gp200)

Autre désignation: Renal Cell Carcinoma

Sujet:

CA-IX, CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, Carbonic dehydratase, G250, Membrane antigen MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250

HeLa cells. Normal kidney or Human Stomach, Rat Stomach or Guinea pig Stomach (WB) renal cell carcinoma (IHC).

Poids moléculaire: 55kDa

ID gène: 768, 63287

UniProt: Q16790