Renal Cell Carcinoma (Gp200) (AA 314-410) anticorps
Aperçu rapide pour Renal Cell Carcinoma (Gp200) (AA 314-410) anticorps (ABIN7863513)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 314-410
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Fonction
- Renal Cell Carcinoma (Carbonic Anhydrase IX) Antibody
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Specificité
- Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human CA9 protein fragment (around aa 314-410) (exact sequence is proprietary)
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Renal Cell Carcinoma (Gp200)
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Autre désignation
- Renal Cell Carcinoma
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Sujet
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CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, G250, Membrane antigen MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250
U87 cells. Normal kidney or renal cell carcinoma (IHC).
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Poids moléculaire
- 55kDa
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ID gène
- 768, 63287
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UniProt
- Q16790
Antigène
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