Recombinant Cathepsin D anticorps

N° du produit ABIN7865162

Cet anticorps Lapin Monoclonal détecte spécifiquement Cathepsin D dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Cathepsin D anticorps (ABIN7865162)

Antigène: Cathepsin D (CTSD)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CTSD-9613R

Détail du produit anti-Cathepsin D anticorps

Expression System: CHO Cells

Fonction: Recombinant Cathepsin D (Tumor Marker) Antibody

Specificité: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: His-tagged CTSD protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: Cathepsin D

Sujet:

CatD, Cathepsin D, Ceroid lipofuscinosis neuronal 10, CLN10, CPSD, Epididymis secretory sperm binding protein Li 130P, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease

Human kidney, liver, lung or breast tissues. Brain, Heart, Skeletal muscle, Skin or Pancreas

Poids moléculaire: 48kDa (Procathepsin D), 34kDa (Cathepsin D), 14kDa (Cathepsin D)

ID gène: 1509, 654447

UniProt: P07339

Pathways: Peptide Hormone Metabolism