Recombinant CDX2 anticorps
Aperçu rapide pour Recombinant CDX2 anticorps (ABIN7865106)
Antigène
Voir toutes CDX2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Expression System
- CHO Cells
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Fonction
- Recombinant CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker) Antibody
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Specificité
- The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids 79oΩand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Recombinant full-length human CDX2 protein
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CDX2 (Caudal Type Homeobox 2 (CDX2))
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Autre désignation
- CDX2
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Sujet
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Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2
HT29 cells. Human colon carcinoma
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Poids moléculaire
- 40kDa
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ID gène
- 1045, 174249
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UniProt
- Q99626
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Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
Antigène
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