Recombinant CD40 anticorps

N° du produit ABIN7857762

L’anticorps anti-CD40 Monoclonal Souris est utilisé pour la détection de CD40 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant CD40 anticorps (ABIN7857762)

Antigène: CD40

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R11E9

Détail du produit anti-CD40 anticorps

Expression System: CHO Cells

Fonction: Recombinant CD40 / TNFRSF5 Antibody

Specificité: The CD40 antigen is a single chain glycoprotein with a calculated molecular weight of 27 kD. It is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin,Ä111s disease-associated antigen, CD30. The precise function of the CD40 antigen is unknown, but it appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation. It is also important in the prevention of apoptosis of germinal centre B cells. The CD40 antigen is found on mature B cells (except plasma cells), interdigitating reticulum cells and follicular dendritic cells.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant fusion protein corresponding to the entire external domain of the CD40 molecule

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet:

TNFRSF5

Human spleen, lymph node or tonsil.

Poids moléculaire: 43kDa

ID gène: 958, 472860

UniProt: P25942

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints