Recombinant TGFBR1 anticorps

N° du produit ABIN7865491

Cet anticorps Souris Monoclonal détecte spécifiquement TGFBR1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant TGFBR1 anticorps (ABIN7865491)

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFBR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RG3E6

Détail du produit anti-TGFBR1 anticorps

Expression System: CHO Cells

Fonction: Recombinant Transforming Growth Factor Beta Receptor 1 (TGFBR1) Antibody

Specificité: Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule

Isotype: IgM, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TGFBR1

Antigène: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Autre désignation: Transforming Growth Factor Beta Receptor 1

Sujet:

ALK5 | SKR4

Human placenta, spleen or liver. HEK293T cells.

Poids moléculaire: 53kDa

ID gène: 7046

UniProt: P36897

Pathways: Growth Factor Binding