Recombinant Desmin anticorps

N° du produit ABIN7862702

Cet anticorps Souris Monoclonal détecte spécifiquement Desmin dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Poulet et Hamster.

Aperçu rapide pour Recombinant Desmin anticorps (ABIN7862702)

Antigène: Desmin (DES)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Souris, Poulet, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RDES-1711

Détail du produit anti-Desmin anticorps

Expression System: HEK-293 Cells

Fonction: Recombinant Desmin (Muscle Cell Marker) Antibody

Specificité: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain °™-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Purification: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Recombinant full-length human desmin protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Human uterus or leiomyosarcoma. Heart, Intestine or RH30.

Poids moléculaire: 52kDa

ID gène: 1674, 594952

UniProt: P17661