CDC5L anticorps (AA 1-148)

N° du produit ABIN7863814

Cet anticorps Souris Monoclonal détecte spécifiquement CDC5L dans IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDC5L anticorps (AA 1-148) (ABIN7863814)

Antigène: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC5L est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PCRP-CDC5L-2C6

Détail du produit anti-CDC5L anticorps

Épitope: AA 1-148

Fonction: CDC5L Antibody

Specificité: Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19,p21;q13.1) with USF-2.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1-148) of human CDC5L protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CDC5L

Antigène: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Autre désignation: CDC5L

Sujet:

CDC5, CDC5 cell division cycle 5-like (S. pombe), Cdc5 related protein, CDC5-LIKE, Cdc5-like protein, Cdc5l, CEF1, Cell division cycle 5-like protein, dJ319D22.1, KIAA0432, PCDC5RP, Pombe Cdc5 related protein

HeLa cells. Ubiquitously expressed in both fetal and adult tissues.

Poids moléculaire: 92kDa

ID gène: 988, 485471

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding