GCET2 anticorps (AA 1-200)

N° du produit ABIN7862873

L’anticorps anti-GCET2 Monoclonal Souris est utilisé pour la détection de GCET2 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour GCET2 anticorps (AA 1-200) (ABIN7862873)

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCET2 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: HGAL-830

Détail du produit anti-GCET2 anticorps

Épitope: AA 1-200

Fonction: HGAL (Human Germinal Center Associated Lymphoma Marker) Antibody

Specificité: Recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (178 Amino acid residues from around aa1-200) of human HGAL protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GCET2

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Autre désignation: HGAL

Sujet:

GCAT2, GCET2 germinal center expressed transcript 2, Germinal center associated lymphoma (hGAL), Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated signaling and motility protein

Daudi, Raji or U266 cells. Human lymphocytes. Human lymph node, tonsil or testis.

Poids moléculaire: 21kDa

ID gène: 257144, 49614

UniProt: Q8N6F7