IL20RA anticorps (AA 1-200)

N° du produit ABIN7864480

Cet anticorps Souris Monoclonal détecte spécifiquement IL20RA dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL20RA anticorps (AA 1-200) (ABIN7864480)

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL20RA est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: IL20RA-1752

Détail du produit anti-IL20RA anticorps

Épitope: AA 1-200

Fonction: IL20RA (Interleukin 20 Receptor Subunit Alpha) Antibody

Specificité: The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-200) of human IL20RA protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur IL20RA

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Autre désignation: IL20RA

Sujet:

class II cytokine receptor ZCYTOR7, CRF2 8, Cytokine receptor class II member 8, Cytokine receptor family 2 member 8, IL 20R1, IL-20 receptor subunit alpha, IL-20R1, IL20 Receptor alpha, Interleukin 20 receptor alpha chain,

brain or psoriatic skin.|Human skin|testis

Poids moléculaire: 90-100kDa

ID gène: 53832, 445868

UniProt: Q9UHF4