Recombinant Kallikrein 7 anticorps (AA 1-200)

N° du produit ABIN7864976

L’anticorps anti-Kallikrein 7 Monoclonal Lapin est utilisé pour la détection de Kallikrein 7 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant Kallikrein 7 anticorps (AA 1-200) (ABIN7864976)

Antigène: Kallikrein 7 (KLK7)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: KLK7-8971R

Détail du produit anti-Kallikrein 7 anticorps

Épitope: AA 1-200

Fonction: Recombinant KLK7 (Kallikrein Related Peptidase 7) Antibody

Specificité: Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13.41. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein or HGK-1, and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. KLK4, KLK5, KLK9, KLK13, KLK12 and KLK14 have been previously known as KLK-L1, KLK-L2, KLK-L3, KLK-L4, KLK-L5 and KLK-L6, respectively. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment of human KLK7 protein (around aa 1-200) (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: KLK7

Sujet:

Chymotryptic stratum corneum, hK7, hSCCE, Kallikrein 7 (chymotryptic stratum corneum), Kallikrein related peptidase 7, Protease serine 6, PRSS6, SCCE, Serine protease 6, Signal protein, Stratum corneum chymotryptic enzyme

Human skin tissue (IHC). liver.

Poids moléculaire: 27kDa

ID gène: 5650, 151254

UniProt: P49862

Pathways: Système du Complément