PAX4 anticorps (AA 1-200)

N° du produit ABIN7858644

L’anticorps anti-PAX4 Monoclonal Souris est utilisé pour la détection de PAX4 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour PAX4 anticorps (AA 1-200) (ABIN7858644)

Antigène: PAX4 (Paired Box 4 (PAX4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PAX4-7599

Détail du produit anti-PAX4 anticorps

Épitope: AA 1-200

Fonction: PAX4 Antibody

Specificité: Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing ≤ cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ≤ cell lines MIN6, ≤ TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur PAX4

Antigène: PAX4 (Paired Box 4 (PAX4))

Autre désignation: PAX4

Sujet:

KPD, MODY9, Paired box 4

DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen

Poids moléculaire: 38kDa

ID gène: 5078, 129706

UniProt: O43316