PLK1 anticorps (AA 1-200)

N° du produit ABIN7864402

L’anticorps anti-PLK1 Monoclonal Souris est utilisé pour la détection de PLK1 dans des échantillons de Humain. Il a été validé pour ELISA et IHC.

Aperçu rapide pour PLK1 anticorps (AA 1-200) (ABIN7864402)

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: PLK1-7122

Détail du produit anti-PLK1 anticorps

Épitope: AA 1-200

Fonction: PLK1 Antibody

Specificité: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment of human PLK1 protein (around aa 1-200) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: PLK1

Sujet:

Cell cycle regulated protein kinase, Polo like kinase 1, Serine/threonine protein kinase 13, Serine/threonine protein kinase PLK1, STPK13

Human tonsil|spleen or thymus.

Poids moléculaire: 66kDa

ID gène: 5347, 592049

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase