PLK1 anticorps (AA 1-200)

N° du produit ABIN7858666

Cet anticorps anti-PLK1 Monoclonal Souris (Clone PLK1-7122) (ABIN7858666) détecte spécifiquement PLK1 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PLK1 anticorps (AA 1-200) (ABIN7858666)

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: PLK1-7122

Détail du produit anti-PLK1 anticorps

Épitope: AA 1-200

Fonction: PLK1 Antibody

Specificité: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment of human PLK1 protein (around aa 1-200) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: PLK1

Sujet:

Cell cycle regulated protein kinase, Polo like kinase 1, Serine/threonine protein kinase 13, Serine/threonine protein kinase PLK1, STPK13

Human tonsil|spleen or thymus.

Poids moléculaire: 66kDa

ID gène: 5347, 592049

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase