Hexokinase 1 anticorps (AA 1-250)
Aperçu rapide pour Hexokinase 1 anticorps (AA 1-250) (ABIN7865350)
Antigène
Voir toutes Hexokinase 1 (HK1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-250
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Fonction
- HK1 / Hexokinase 1 Antibody
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Specificité
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa1-250) of human HK1 protein (exact sequence is proprietary)
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Hexokinase 1 (HK1)
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Autre désignation
- HK1
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Sujet
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Neuropathy, hereditary motor and sensory, Russe type
Human brain.
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Poids moléculaire
- 102kDa
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ID gène
- 3098, 370365
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UniProt
- P19367
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Pathways
- Carbohydrate Homeostasis, L'effet Warburg
Antigène
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