Syndecan 1 anticorps (AA 1-250)

N° du produit ABIN7858778

Cet anticorps Souris Monoclonal détecte spécifiquement Syndecan 1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Syndecan 1 anticorps (AA 1-250) (ABIN7858778)

Antigène: Syndecan 1 (SDC1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: SDC1-7177

Détail du produit anti-Syndecan 1 anticorps

Épitope: AA 1-250

Fonction: CD138 / Syndecan-1 (SDC1) (Plasma Cell Marker) Antibody

Specificité: CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa1-250) of human CD138 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: CD138

Sujet:

Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor, SDC1, SYND1, Syndecan Proteoglycan 1, Syndecan-1 79oΩ

Human tonsil or lymph node.

Poids moléculaire: 85kDa

ID gène: 6382, 224607

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism