S100P anticorps (AA 1-95)
Aperçu rapide pour S100P anticorps (AA 1-95) (ABIN7864121)
Antigène
Voir toutes S100P AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-95
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Fonction
- S100P / MIG9 Antibody
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Specificité
- S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa1-95) of human MIG9 protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- S100P (S100 Calcium Binding Protein P (S100P))
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Autre désignation
- S100P
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Sujet
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Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P
Human pancreatic adenocarcinoma|placenta or spleen tissue.
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Poids moléculaire
- 10kDa
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ID gène
- 6286, 2962
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UniProt
- P25815
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Pathways
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
Antigène
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