Recombinant TPSAB1 anticorps (AA 100-250)

N° du produit ABIN7858969

Cet anticorps anti-TPSAB1 Monoclonal Souris (Clone rTPSAB1-1963) (ABIN7858969) détecte spécifiquement TPSAB1 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant TPSAB1 anticorps (AA 100-250) (ABIN7858969)

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TPSAB1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RTPSAB1-1963

Détail du produit anti-TPSAB1 anticorps

Épitope: AA 100-250

Fonction: Recombinant Tryptase (Mast Cell Marker) Antibody

Specificité: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human Tryptase protein fragment (around aa 100-250) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur TPSAB1

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Autre désignation: Tryptase

Sujet:

Lung Tryptase, Mast cell alpha II Tryptase, Mast cell beta I Tryptase, Mast cell protease 7, Mast cell protease II, MCP7, Pituitary Tryptase, Skin Tryptase, TPS1, TPSAB1, TPSB1, Tryptase 1, Tryptase alpha 1, Tryptase skin

Human skin or tonsil.

Poids moléculaire: 31-36kDa

ID gène: 7177, 405479

UniProt: Q15661