MBP anticorps (AA 119-131)

N° du produit ABIN7863113

L’anticorps anti-MBP Monoclonal Souris est utilisé pour la détection de MBP dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye et Hamster. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour MBP anticorps (AA 119-131) (ABIN7863113)

Antigène: MBP (Myelin Basic Protein (MBP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: MBP-4272

Détail du produit anti-MBP anticorps

Épitope: AA 119-131

Fonction: Myelin Basic Protein Antibody

Specificité: Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30 % of the total protein and about 10 % of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4272 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recognizes bovine BMP, in the region of residues 119-131 (GAEGQRPGFGYGG).

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MBP

Antigène: MBP (Myelin Basic Protein (MBP))

Autre désignation: Myelin Basic Protein

Sujet:

GDB, Golli MBP, myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MLD, Myelin A1 Protein, basic, Myelin Deficient, Myelin membrane encephalitogenic protein, SHI, Shiverer, SP

U87 cells. Human brain or astrocytoma tissue. Mouse Brain, Rat Brain, Guinea pig Brain or Hamster Brain

Poids moléculaire: 14-22kDa

ID gène: 4155, 551713

UniProt: P02686