Reelin anticorps (AA 1796-2115)

N° du produit ABIN7862732

Cet anticorps Souris Monoclonal détecte spécifiquement Reelin dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rongeurs.

Aperçu rapide pour Reelin anticorps (AA 1796-2115) (ABIN7862732)

Antigène: Reelin (RELN)

Reactivité: Humain, Souris, Rongeurs

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reelin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: RELN-4498

Détail du produit anti-Reelin anticorps

Épitope: AA 1796-2115

Fonction: Reelin Antibody

Specificité: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1796-2115) of human RELN protein

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Reelin

Antigène: Reelin (RELN)

Autre désignation: Reelin

Sujet:

LIS2, PRO1598, Reeler, Reelin, RELN, RELN_HUMAN, RL

Human or mouse brain or CNS.

Poids moléculaire: 387.5kDa

ID gène: 19699, 655654

UniProt: P78509

Pathways: Synaptic Membrane