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OLIG2 anticorps (AA 200-313)

Cet anticorps anti-OLIG2 Monoclonal Souris (Clone rOLIG2-8884) (ABIN7864430) détecte spécifiquement OLIG2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.
N° du produit ABIN7864430
687,58 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 10 jours ouvrables

Aperçu rapide pour OLIG2 anticorps (AA 200-313) (ABIN7864430)

Antigène

Voir toutes OLIG2 Anticorps
OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivité

  • 113
  • 55
  • 51
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 97
  • 30
Souris

Clonalité

  • 64
  • 63
Monoclonal

Conjugué

  • 75
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp OLIG2 est non-conjugé

Application

  • 63
  • 55
  • 35
  • 23
  • 16
  • 14
  • 13
  • 13
  • 11
  • 10
  • 8
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

Clone

ROLIG2-8884
  • Épitope

    • 17
    • 16
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-313

    Fonction

    OLIG2 (Marker of Glial Brain Tumors) Antibody

    Specificité

    Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).

    Purification

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    Immunogène

    Recombinant fragment of human OLIG2 protein (around aa 200-313) (exact sequence is proprietary)

    Isotype

    IgG2b, kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • Antigène

    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

    Autre désignation

    OLIG2

    Sujet

    Basic helix loop helix protein class B1 (bHLHB1), basic helix-loop-helix protein 19 (bHLHe19), OLIG2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, Protein kinase C-binding protein 2 (PRKCBP2), RACK17

    THP-1 cells. Human brain or astrocytoma.

    Poids moléculaire

    30-40kDa

    ID gène

    10215, 176977
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