IDO2 anticorps (AA 200-350)

N° du produit ABIN7862706

Cet anticorps Souris Monoclonal détecte spécifiquement IDO2 dans ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IDO2 anticorps (AA 200-350) (ABIN7862706)

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: IDO2-2639

Détail du produit anti-IDO2 anticorps

Épitope: AA 200-350

Fonction: IDO2 / Indoleamine 2,3-dioxygenase 2 Antibody

Specificité: IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 200-350) of human IDO2 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IDO2

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Autre désignation: IDO2

Sujet:

3-dioxygenase 2, 3-dioxygenase-like protein 1, EC 1.13.11., INDOL 1, Indoleamine 2, Indoleamine 2,3 dioxygenase 2, Indoleamine 2,3 dioxygenase like 1 protein, Indoleamine pyrrole 2,3 dioxygenase like 1, Indoleamine-pyrrole 2

Human placenta or liver.

Poids moléculaire: 47kDa

ID gène: 169355, 676257

UniProt: Q6ZQW0