Recombinant PAX2A anticorps (AA 223-354)

N° du produit ABIN7859571

L’anticorps anti-PAX2A Monoclonal Lapin est utilisé pour la détection de PAX2A dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant PAX2A anticorps (AA 223-354) (ABIN7859571)

Antigène: PAX2A (Paired Box Gene 2a (PAX2A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX2A est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PAX2-8671R

Détail du produit anti-PAX2A anticorps

Épitope: AA 223-354

Fonction: Recombinant PAX2 (Renal Cell & Ovarian Carcinoma Marker) Antibody

Specificité: Recognizes a protein of 42kDa, which is identified as PAX2. It is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and mullerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cell carcinoma and ovarian carcinoma by immunohistochemistry.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 223-354) of human PAX2 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PAX2A

Antigène: PAX2A (Paired Box Gene 2a (PAX2A))

Autre désignation: PAX2

Sujet:

Paired box 2, paired box protein 2, Paired box protein Pax-2, Paired box protein Pax2, PAX2

NAMALWA cells. Human fetal kidney|renal cell carcinoma (RCC) or ovarian carcinoma.

Poids moléculaire: 42kDa

ID gène: 5076, 155644

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation