Recombinant Desmin anticorps (AA 270-470)

N° du produit ABIN7864214

L’anticorps anti-Desmin Monoclonal Lapin est utilisé pour la détection de Desmin dans des échantillons de Humain, Rat, Poulet et Hamster. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Desmin anticorps (AA 270-470) (ABIN7864214)

Antigène: Desmin (DES)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Poulet, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: DES-8610R

Détail du produit anti-Desmin anticorps

Épitope: AA 270-470

Fonction: Recombinant Desmin (Muscle Cell Marker) Antibody

Specificité: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain ±-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. 79oΩAntibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. 79oΩ

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 270-470) of human DES protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Intestine, Human uterus or leiomyosarcoma.

Poids moléculaire: 52kDa

ID gène: 1674, 594952