Recombinant STAR anticorps (AA 39-108)

N° du produit ABIN7863433

Cet anticorps anti-STAR Monoclonal Lapin (Clone STAR-3915R) (ABIN7863433) détecte spécifiquement STAR dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant STAR anticorps (AA 39-108) (ABIN7863433)

Antigène: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STAR est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: STAR-3915R

Détail du produit anti-STAR anticorps

Épitope: AA 39-108

Fonction: Recombinant StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Antibody

Specificité: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 39-108) of human STAR protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur STAR

Antigène: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Autre désignation: StAR

Sujet:

Cholesterol trafficker, Luteinizing hormone induced protein, Mitochondrial steroid acute regulatory protein, StAR, StAR related lipid transfer (START) domain containing 1, StARD1, START domain-containing protein 1, Steroid acute regulatory protein, Steroidogenic acute regulator (STAR), Steroidogenic acute regulatory protein mitochondrial

K-562 cells. Human adrenal or testicular carcinoma.

Poids moléculaire: 30kDa

ID gène: 6770, 521535

UniProt: P49675

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis