MX1 anticorps (AA 400-592)

N° du produit ABIN7864356

Cet anticorps Souris Monoclonal détecte spécifiquement MX1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MX1 anticorps (AA 400-592) (ABIN7864356)

Antigène: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MX1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MX1-7529

Détail du produit anti-MX1 anticorps

Épitope: AA 400-592

Fonction: MX1 / MX dynamin like GTPase 1 Antibody

Specificité: The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-a/IFN-b. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-a/IFN-b, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa400-592) of human MX1 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur MX1

Antigène: MX1 (Myxovirus Resistance Protein 1 (MX1))

Autre désignation: MX1

Sujet:

Human interferon regulated resistance GTP binding protein MXA, IFI78K, Interferon induced GTP binding protein Mx1, Interferon inducible protein p78, Interferon regulated resistance GTP binding protein MxA, MxA, Myxoma resistance protein 1, Myxovirus (influenza virus) resistance 1 interferon inducible, N-terminally processed

breast cancer or colon cancer tissues.|Human spleen|Tonsil

Poids moléculaire: 72kDa

ID gène: 4599, 517307

UniProt: P20591