Recombinant CD34 anticorps (AA 50-250)

N° du produit ABIN7860241

Cet anticorps anti-CD34 Monoclonal Souris (Clone rICO-115) (ABIN7860241) détecte spécifiquement CD34 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD34 anticorps (AA 50-250) (ABIN7860241)

Antigène: CD34

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RICO-115

Détail du produit anti-CD34 anticorps

Épitope: AA 50-250

Fonction: Recombinant CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody

Specificité: This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into 79oΩthree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain.CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa50-250) of human CD34 protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet:

Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin

Jurkat or KG-1 cells. Human tonsil or angiosarcoma.

Poids moléculaire: 90-110kDa

ID gène: 947, 374990

UniProt: P28906