Recombinant Transferrin Receptor anticorps (AA 50-250)
Aperçu rapide pour Recombinant Transferrin Receptor anticorps (AA 50-250) (ABIN7860275)
Antigène
Voir toutes Transferrin Receptor (TFRC) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 50-250
-
Fonction
- Recombinant CD71 / Transferrin Receptor (TFRC) (Extracellular Domain) Antibody
-
Specificité
- It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
-
Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- Recombinant human fragment (around aa50-250) of human TFRC protein (exact sequence is proprietary)
-
Isotype
- IgG, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
-
Autre désignation
- CD71
-
Sujet
-
Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR
Human placenta, lungs or bone marrow, PC-3 cell lysate
-
Poids moléculaire
- 85-95kDa (monomer), 190kDa (dimer)
-
ID gène
- 7037, 529618
-
UniProt
- P02786
-
Pathways
- Transition Metal Ion Homeostasis
Antigène
-