TdT anticorps (AA 52-192)

N° du produit ABIN7862714

Cet anticorps Souris Monoclonal détecte spécifiquement TdT dans ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TdT anticorps (AA 52-192) (ABIN7862714)

Antigène: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TdT est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: DNTT-1453

Détail du produit anti-TdT anticorps

Épitope: AA 52-192

Fonction: TdT / DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Antibody

Specificité: Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3'-hydroxyl end of DNA primers without template direction. The enzyme thus provides a unique method for the labeling of the 3' termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 52-192) of human DNTT protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TdT

Antigène: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Autre désignation: TdT

Sujet:

Deoxynucleotidyltransferase terminal, DNA Nucleotidylexotransferase, DNTT, Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase, Terminal transferase

Human thymus. Jurkatcells.

Poids moléculaire: 58kDa

ID gène: 1791, 534206

UniProt: P04053

Pathways: Réparation de l'ADN