TEK anticorps (AA 700-1000)
Aperçu rapide pour TEK anticorps (AA 700-1000) (ABIN7865450)
Antigène
Voir toutes TEK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 700-1000
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Fonction
- CD202b / TIE2 / TEK (Tyrosine Kinase with Ig and EGF Homology Domains 2) Antibody
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Specificité
- This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa700-1000) of human TEK protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Autre désignation
- CD202b
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Sujet
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TIE2, VMCM, GLC3E, TIE-2, VMCM1, CD202B
Human lung, placenta or spleen.
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Poids moléculaire
- 65kDa
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ID gène
- 7010
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UniProt
- Q02763
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Pathways
- Signalisation RTK, Growth Factor Binding
Antigène
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