Neuropilin 1 anticorps (AA 700-900)

N° du produit ABIN7860594

L’anticorps anti-Neuropilin 1 Monoclonal Souris est utilisé pour la détection de Neuropilin 1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Neuropilin 1 anticorps (AA 700-900) (ABIN7860594)

Antigène: Neuropilin 1 (NRP1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuropilin 1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: NRP1-4620

Détail du produit anti-Neuropilin 1 anticorps

Épitope: AA 700-900

Fonction: NRP1 / Neuropilin-1 Antibody

Specificité: Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa700-900) of human NRP1 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: NRP1

Sujet:

A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD304, Neuropilin-1, Neuropilin1, NP1, NPN1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R

Human placenta|kidney or lymph node.|testis

Poids moléculaire: 130kDa

ID gène: 8829, 131704

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals