Recombinant Calnexin anticorps (N-Term)

N° du produit ABIN7863825

Cet anticorps anti-Calnexin Monoclonal Lapin (Clone CANX-9147R) (ABIN7863825) détecte spécifiquement Calnexin dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Calnexin anticorps (N-Term) (ABIN7863825)

Antigène: Calnexin (CANX)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Calnexin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: CANX-9147R

Détail du produit anti-Calnexin anticorps

Épitope: AA 1-300, N-Term

Fonction: Recombinant Calnexin (Endoplasmic Reticulum Marker) Antibody

Specificité: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Calnexin

Antigène: Calnexin (CANX)

Autre désignation: Calnexin

Sujet:

Calnexin, CANX, CNX, IP90, Major histocompatibility complex class I antigen-binding protein p88, P90

HeLa|MCF-7 or U2OS cells. Kidney or small intestine. Brain, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Skin, Skeletal muscle and Stomach

Poids moléculaire: 90kDa

ID gène: 821, 567968

UniProt: P27824

Pathways: Signalisation MAPK, Thyroid Hormone Synthesis