Recombinant YWHAE anticorps
Aperçu rapide pour Recombinant YWHAE anticorps (ABIN7860832)
Antigène
Voir toutes YWHAE AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant 14-3-3E / Tryptophan 5-Monooxygenase Antibody
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Specificité
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human full-length YWHAE protein
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- YWHAE (14-3-3 epsilon (YWHAE))
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Autre désignation
- 14-3-3E
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Sujet
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MDS, epididymis luminal protein 2, mitochondrial import stimulation factor (MSF) L subunit, Mitochondrial import stimulation factor L subunit, MSF L, protein kinase C inhibitor protein-1
HEK-293 or A-431 cell lines. Human brain|prostate or placenta.
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Poids moléculaire
- 29.4kDa
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ID gène
- 7531, 513851
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UniProt
- P62258
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Pathways
- Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
Antigène
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