Recombinant Actin anticorps
Aperçu rapide pour Recombinant Actin anticorps (ABIN7860841)
Antigène
Voir toutes Actin (ACTA1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Actin alpha 1, Skeletal Muscle Antibody
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Specificité
- All eukaryotic cells express Actin, which often constitutes as much as 50 % of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. a-Actin expression is limited to various types of muscle, whereas b and g are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion, Rac regulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human ACTA1 protein
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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Autre désignation
- Actin alpha 1, Skeletal Muscle
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Sujet
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a actin, ACTA, ACTA1, Actin, alpha skeletal muscle, ACTS_HUMAN, Alpha actin 1, Alpha-actin-1, ASMA, MPFD, Skeletal muscle alpha actin 1
Human Intestine, Mouse Intestine, Rat Intestine, Hamster Intestine, Guinea pig Intestine, Human skeletal muscle, Mouse skeletal muscle, Rat skeletal muscle, Hamster skeletal muscle or Guinea pig skeletal muscle
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Poids moléculaire
- 43kDa
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ID gène
- 58, 1288
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UniProt
- P68133
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Pathways
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Antigène
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