Recombinant AKR1B1 anticorps

N° du produit ABIN7862817

Cet anticorps anti-AKR1B1 Monoclonal Souris (Clone rAKR1B1-7295) (ABIN7862817) détecte spécifiquement AKR1B1 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant AKR1B1 anticorps (ABIN7862817)

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AKR1B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: RAKR1B1-7295

Détail du produit anti-AKR1B1 anticorps

Fonction: Recombinant Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) Antibody

Specificité: AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length AKR1B1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur AKR1B1

Antigène: AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))

Autre désignation: Aldo-keto Reductase Family 1 Member B1

Sujet:

AKR1B1, Aldehyde reductase, aldehyde reductase 1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, AR, Lii5-2 CTCL tumor antigen, low Km aldose reductase

HEK293, HeLa, MOLT4, Jurkat or Raji cells. Human kidney or colon carcinoma.

Poids moléculaire: 37kDa

ID gène: 231, 521212

UniProt: P15121

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process